Volume 01 is a saffron extract supplement made with 28 mg of Affron® per capsule.

Affron® is a patented, water-extracted dry saffron extract by Pharmactive made from the stigmas of Crocus sativus L.

It is standardized by HPLC to contain at least 3.5% Lepticrosalides®—a complex of saffron’s naturally occurring bioactive compounds, including crocins, picrocrocin and safranal. At the 28 mg dose used in Volume 01, that represents at least 0.98 mg of standardized Lepticrosalides®.

This standardization helps maintain a consistent profile from batch to batch and ensures that Volume 01 uses the same specific form of saffron evaluated in Affron® clinical studies.

28 milligrams is the daily dose evaluated in Affron® clinical studies. Each Volume 01 capsule provides that studied dose.

A nootropic is a substance that supports aspects of mental function, such as focus, memory or mood.

Saffron is considered a botanical nootropic and has been studied for its effects on mood, stress and cognitive wellbeing.

Antioxidants are compounds that help neutralize free radicals: unstable molecules produced through normal processes in the body and through exposure to environmental factors.

Saffron naturally contains antioxidant compounds, including crocins, which contribute to its characteristic color and bioactive profile.

Each capsule contains:

• Affron® saffron extract — 28 mg
• Rice flour — used to support formula stability and the even distribution of Affron® throughout each capsule
• Hypromellose — a plant-based capsule shell

That’s the full formula.

Rice flour helps keep the formula stable and supports the even distribution of Affron® throughout each capsule. It is the only inactive ingredient inside the capsule shell.

More ingredients don’t necessarily mean better results. We focus on one carefully selected active ingredient, with a clearly stated source, dose and supporting research. 

Not all saffron extracts are created equal. Volume 01 uses Affron®, a clinically studied saffron extract standardized to contain at least 3.5% Lepticrosalides®. This helps ensure consistent potency from batch to batch, rather than leaving you guessing what you’re getting.

Take one capsule daily, preferably with food, or as suggested by your physician. Use consistently.

Store in a cool, dry place away from direct sunlight.

Affron® is not a stimulant and is not expected to feel immediate. Clinical studies generally lasted between four and 12 weeks, so consistent daily use is important.

Individual experiences may vary.

If you take medication, have a medical condition, are pregnant or nursing, speak with a qualified healthcare professional before use.

Volume 01 is vegan, gluten-free, non-GMO and preservative-free.

If you have a specific allergy or dietary requirement, email support@indexwellness.co or speak with your physician before use.

We take quality seriously. Volume 01 is manufactured in an FDA-registered facility and undergoes independent third-party testing for heavy metals, including lead, arsenic, mercury and cadmium, as well as microbial contaminants such as E. coli and Salmonella.

These tests help us verify the purity of our product and ensure we’re keeping the things you don’t want out of your daily routine.

Affron® is developed and manufactured by Pharmactive. We selected it for its standardization, quality and body of clinical evidence.

We currently ship within the United States only.

Standard U.S. shipping is free on orders of $50 or more. Shipping rates for orders below $50 are shown at checkout.

Orders typically arrive within 5–8 business days of being placed, including order processing and transit. Delivery times are estimates and may vary by destination, holidays or carrier delays. You’ll receive tracking information once your order ships.

Use the tracking link in your shipping confirmation email. If you have trouble locating your order, email support@indexwellness.co with your order number.

We want you to give INDEX a try. And if it’s not for you, that’s okay too. 

Your first bottle is covered by our 30-day satisfaction guarantee, even if you’ve already opened it. Simply email support@indexwellness.co within 30 days of delivery with your order number.

The guarantee applies to one bottle per customer from their first order placed on indexwellness.co, including orders containing multiple bottles. Subsequent purchases are not eligible.

We’ll refund the amount paid for the eligible bottle, after any discounts, to your original payment method. Shipping charges are non-refundable. We’ll notify you once your refund has been processed.

We’re sorry if something isn’t quite right with your order! Please email us at support@indexwellness.co with your order number and a photo of the issue.

We’ll review the details and work with you to make it right, whether that’s a replacement or refund for the affected item, at no additional cost.

Please reach out to us before sending anything back.

Changed your mind? Just email us at support@indexwellness.co as soon as possible, and we’ll do our best to help. We can only make changes or cancellations before your order ships, so we can’t guarantee we’ll be able to catch it in time.

Email support@indexwellness.co and include your order number when relevant.